Tailored cytomegalovirus can help T cells detect more SIV

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According to a new study, a designed cytomegalovirus (CMV) has fundamentally changed the activity of T cells to protect rhesus monkeys from SIV infection; SIV in monkeys is equivalent to human HIV.

Scott Hansen and colleagues have recently reported a CMV strain designed to express certain SIV proteins, so that vaccinated monkeys can control SIV infection. Now they report that this particular vaccine vector will drive A very unique immune response from CD8 + T cells. They said that when they met the designed CMV strain called 68-1 RhCMV, CD8 + T cells would initiate a much stronger response than their usual immune response to SIV. In the presence of 68-1 RhCMV, CD8 + T cells can target the epitope of SIV—or a small fragment of an antigenic protein—and these antigenic epitopes usually avoid Designed viral vectors or immune responses stimulated only by SIV infection. According to the researchers, CD8 + T cells usually only respond to antigens presented by cells belonging to the major histocompatibility complex of class I-or MHC-I, but 68-1 RhCMV produces anti-MHC-I CD8 + T cells react with MHC-II molecules.

Their results show that CMV vectors can affect CD8 + T cells by genetic programming so that they can recognize a wider range of SIV epitopes. These findings may eventually lead to more effective treatments for HIV, and a "Viewpoint" article by Nilu Goonetilleke and Andrew McMichael explains these results in more detail.

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Magnetic Receptive Whiteboard Sheet is one kind of flexible whiteboard. It is easy cut, bent, twisted, coiled, or can machined into almost any shape. So it can be roll up to saving space and carry easily.

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Magnetic Receptive Whiteboard Sheet has excellent write-on and wipe-off durability. Premium PET base, good weather resistance. It is compatible for many kinds pen, like dry erased whiteboard marker, easy to write and wipe. For normal whiteboard marker pen, marks can be dry erased off within one month. If the marks leave on a whiteboard for long enough and can`t be dry erased, please use whiteboard cleaner or some alcoholic liquid to get them off.

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Many Creative Application 

Magnetic Receptive Whiteboard Sheet is made of premium PET and steel sheeting. Steel sheeting is made by mixing iron powder with plastic (CPE etc.). It has excellent magnetic receptive ability. This whiteboard film is becoming increasing popular for the use as Whiteboard Wall or magnetic wall paper. This whiteboard sheecan be exchanged and / or replaced when applied to a wall that has a layer of our magnetic sheeting with adhesive. Restaurants, businesses, preschools and home owners can easily change their wall paper according to their mood, holiday, or season. Multiple layers can be applied to create attractive designs and decors. The versatility of this product creates many different decorating and advertising possibilities. 

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1.Self Adhesive Whiteboard is made of strong adhesive, so the Whiteboard Sticker easy to install and won't fall off easily. The steel sheeting of whiteboard has a certain thickness so that it does install with no wrinkles and no bubbles. No need to drill holes in you wall and can be install any smooth surface like desk,cabinet and so on. By the way,Magnetic Whiteboard Sheet is suitable to install on our Magnetic Receptive Whiteboard Sheet for replace the old Self Adhesive Whiteboard.

2.Removable Adhesive Whiteboard is made of high quality reusable adhesive, added removal for on-the-go mobility to the Self Adhesive Whiteboard. If the adhesive surface is dirty, it will still be sticky after washing.

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